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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Equine protozoal myeloencephalitis ： ウィキペディア英語版 Equine protozoal myeloencephalitis Equine protozoal myeloencephalitis (EPM), is a disease caused by the apicomplexan parasite ''Sarcocystis neurona'' that affects the central nervous system of horses. ==History== EPM was first discovered in the 1960s by the American biologist Dr. Jim Rooney. The disease is considered rare, though recently, an increasing number of cases have been reported. research identified the "barn cat" as the definitive host of the disease. However since that time it has been learned that all wildlife can be a host and the definitive host is not known. Although opossums were once thought to be the definitive host, horses in the Rocky Mountains have been found with EPM where no opossum has ever lived or been. The term EPM refers to the clinical neurologic symptoms caused by the parasite, not infection itself. The majority of horses infected with S. neurona do not exhibit neurologic symptoms consistent with EPM. There are six subspecies of S. neurona which can be identified by surface antigens (SAG). Equine EPM is caused by the parasites that exhibit SAG1, SAG5, and SAG6. SAG1 and SAG5 are responsible for the majority of EPM cases in horses. Horses produce antibodies to these surface antigens. Serum antibody testing is available that measures levels of these antibodies in the blood of horses, which is helpful in diagnosing EPM in an ataxic horse. Serial blood levels are helpful in guiding treatment. In experimentally infected horses it takes 17 days from infection to positive antibody tests. 80% of horses with EPM have positive antibody tests. A negative antibody test in the presence of EPM results if testing is done before 17 days or if the horse has been treated with antiprotozoal drugs which delays antibody production. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Equine protozoal myeloencephalitis」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.